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Количественный анализ восхождение дефектов в Drosophila модели нейродегенеративных расстройств
Journal JoVE
Neurosciences
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Journal JoVE Neurosciences
Quantitative Analysis of Climbing Defects in a Drosophila Model of Neurodegenerative Disorders
DOI:

06:30 min

June 13, 2015

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Chapitres

  • 00:05Titre
  • 01:27Fly Collection and Climbing Assay
  • 03:57Analysis of Fly Performance
  • 04:54Results: Climbing Deficits in a Drosophila Model of Neurodegenerative Disorders
  • 06:01Conclusion

Summary

Traduction automatique

We present an optimized inexpensive and reliable negative geotaxis assay in Drosophila melanogaster as a model for neurodegenerative disorders. Being more sensitive to mild locomotor defects, this assay will help screen for potential genetic interactions and drug targets.

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