Waiting
Traitement de la connexion…

Trial ends in Request Full Access Tell Your Colleague About Jove
Journal / Immunology and Infection / Automated Cell Enrichment of…
JoVE Journal
Immunology and Infection

Un abonnement à JoVE est nécessaire pour afficher ce contenu. Connectez-vous ou commencez votre essai gratuit.

JoVE Journal Immunology and Infection
Automated Cell Enrichment of Cytomegalovirus-specific T cells for Clinical Applications using the Cytokine-capture System
 

Automated Cell Enrichment of Cytomegalovirus-specific T cells for Clinical Applications using the Cytokine-capture System

Article DOI: 10.3791/52808-v • 10:24 min • October 5th, 2015
October 5th, 2015 •
*1, *1, 1, 1, 1, 2, 2, 1
1Division of Pediatrics, U.T. MD Anderson Cancer Center, 2Stem Cell Transplantation and Cellular Therapy, U.T. MD Anderson Cancer Center
* These authors contributed equally

Chapitres

résumé
Automatic Translation

The goal of this protocol is to manufacture pathogen-specific clinical-grade T cells using a bench-top, automated, second generation cell enrichment device that incorporates a closed cytokine capture system and does not require dedicated staff or use of a GMP facility. The cytomegalovirus pp65-specific-T cells generated can be directly administered to patients.

Tags

Automated Cell Enrichment Cytomegalovirus-specific T Cells Clinical Applications Cytokine-capture System Allogeneic Hematopoietic Stem-Cell Transplantation Viral-specific T Cells Gamma-interferon Cytokine Capture System (CCS) CliniMACS Prodigy Magnetic Activated Cell Sorting CMV Pp65-specific T Cells Automated Cell Enrichment Device GMP Facilities Blood Banking Facilities
Read Article

Get cutting-edge science videos from JoVE sent straight to your inbox every month.

Waiting X
Simple Hit Counter