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דגם של רקמות עצביות מקוטב מבוסס משי-קולגן מהונדס 3D
Journal JoVE
Bio-ingénierie
This content is Free Access.
Journal JoVE Bio-ingénierie
Engineered 3D Silk-collagen-based Model of Polarized Neural Tissue
DOI:

06:17 min

October 23, 2015

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Chapitres

  • 00:05Titre
  • 01:16Preparation of Porous Scaffolds from Silk Solution
  • 02:50Seeding the Scaffold with Cells and Collagen Overlay
  • 04:45Results: A 3D Brain-like Tissue Model
  • 05:56Conclusion

Summary

Traduction automatique

Insight into the complex actions of the brain requires advanced research tools. Here we demonstrate a novel silk-collagen-based 3D engineered model of neural tissue resembling brain-like architecture. The model can be used to study neuronal network assembly, axonal guidance, cell-cell interactions and electrical activity.

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