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Chapitres
- 00:05Titre
- 01:40Transient Cerebral Hypoxia-ischemia
- 03:54Laser Speckle Contrast Imaging (LSCI)
- 04:43Tissue Plasminogen Activator (tPA) Administration and Brian Damage Detection
- 05:28Conclusion
Thromboembolic stroke models are vital tools for optimizing the recanalization therapy. Here we report a murine thrombotic stroke model based on transient cerebral hypoxic-ischemic (tHI) insult, which triggers thrombosis and infarction, and responds favorably to tissue plasminogen activator (tPA)-mediated fibrinolysis in a therapeutic window similar to those in stroke patients.
