Journal
/
Médecine
/
A Method of Trigonometric Modelling of Seasonal Variation Demonstrated with Multiple Sclerosis Relapse Data
Journal JoVE
Médecine
Un abonnement à JoVE est nécessaire pour voir ce contenu.  Connectez-vous ou commencez votre essai gratuit.
Journal JoVE Médecine
A Method of Trigonometric Modelling of Seasonal Variation Demonstrated with Multiple Sclerosis Relapse Data

A Method of Trigonometric Modelling of Seasonal Variation Demonstrated with Multiple Sclerosis Relapse Data

DOI:
10.3791/53169-v

•

10:46 min

•

December 09, 2015

•

, , ,
1Department of Neurology,Royal Melbourne Hospital, 2Department of Medicine (RMH),The University of Melbourne, 3Department of Neurology,Ulster Hospital, 4National Centre for Epidemiology and Population Health,Australian National University

Chapitres

  • 00:05Titre
  • 01:06Preparing the Observed Relapse Onset Data
  • 03:10Building a Model
  • 04:40Estimating the Peak Relapse Probability
  • 05:26Modeling the Ultraviolet Radiation Data (UVR)
  • 07:05Modeling UVR-trough-to-relapse-peak Lag
  • 08:34Results: MS-patient Seasonal Relapse with an Equatorial Effect
  • 09:50Conclusion

Summary

Traduction automatique

Traduction automatique

Combining plot analysis with trigonometric regression is a robust method for exploring complex, cyclical phenomena such as relapse onset timing in multiple sclerosis (MS). This method enabled unbiased characterisation of seasonal trends in relapse onset permitting novel inferences around the influence of seasonal variation, ultraviolet radiation (UVR) and latitude.

Tags

Seasonal VariationTrigonometric Regression ModelingMultiple SclerosisRelapse DataStataPlot AnalysisStatistical Regression ModelingSeasonal InfluenceLatitudinal InfluenceRelapse ProbabilityConfoundersBest-fit Convergence

Article

Embed

AJOUTER À LA PLAYLIST

Usage Statistics

Vidéos Connexes

check_url/fr/53169?article_type=v

A Protocol for Comprehensive Assessment of Bulbar Dysfunction in Amyotrophic Lateral Sclerosis (ALS)
check_url/fr/53169?article_type=v

Utility of Dissociated Intrinsic Hand Muscle Atrophy in the Diagnosis of Amyotrophic Lateral Sclerosis
check_url/fr/53169?article_type=v

The Multiple Sclerosis Performance Test (MSPT): An iPad-Based Disability Assessment Tool
check_url/fr/53169?article_type=v

Adapted Resistance Training Improves Strength in Eight Weeks in Individuals with Multiple Sclerosis
check_url/fr/53169?article_type=v

A Protocol for the Use of Remotely-Supervised Transcranial Direct Current Stimulation (tDCS) in Multiple Sclerosis (MS)
check_url/fr/53169?article_type=v

Bioluminescence and Near-infrared Imaging of Optic Neuritis and Brain Inflammation in the EAE Model of Multiple Sclerosis in Mice
check_url/fr/53169?article_type=v

High-Throughput Analysis of Optical Mapping Data Using ElectroMap
check_url/fr/53169?article_type=v

Precision Implementation of Minimal Erythema Dose (MED) Testing to Assess Individual Variation in Human Inflammatory Response
check_url/fr/53169?article_type=v

A Pre-clinical Rat Model for the Study of Ischemia-reperfusion Injury in Reconstructive Microsurgery
check_url/fr/53169?article_type=v

Imaging Features of Systemic Sclerosis-Associated Interstitial Lung Disease

Read Article