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이온 성 액체에 의해 매개 1,6- Ketoesters의 높은 입체 선택적 합성 : 저 분자량 젤 레이터의 새로운 클래스에 빠른 액세스를 가능하게하는 3 요소 반응
Journal JoVE
Chimie
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Journal JoVE Chimie
Highly Stereoselective Synthesis of 1,6-Ketoesters Mediated by Ionic Liquids: A Three-component Reaction Enabling Rapid Access to a New Class of Low Molecular Weight Gelators
DOI:

06:31 min

November 27, 2015

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Chapitres

  • 00:05Titre
  • 01:14Gram-scale Synthesis of Methyl 6-oxo-3,4,6-triphenylhexanoate
  • 03:34Recycling of EMIMAc and Gelation
  • 04:36Results: Analysis of Three-component Synthesis of 1,6-Ketoester
  • 05:35Conclusion

Summary

Traduction automatique

Ionic liquids (ILs) mediate fast, simple and cheap access to 1,6-ketoesters in high diastereoselectivities and good yields. The reaction protocol is robust and the 1,6-ketoesters can be obtained in gram scale after a simple filtration protocol. Moreover, the 1,6-ketoesters are potent gelators in hydrocarbon solvents.

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