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Journal / Biology / 药物与DNA相互作用的细胞全基因组映射与COSMIC（小分子交联，染色质隔离）…
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药物与DNA相互作用的细胞全基因组映射与COSMIC（小分子交联，染色质隔离）
 
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药物与DNA相互作用的细胞全基因组映射与COSMIC（小分子交联，染色质隔离）

Article DOI: 10.3791/53510-v • 10:05 min • January 20th, 2016
January 20th, 2016 •
1, 1, 1,2, 3, 1, 1,4
1Department of Biochemistry, University of Wisconsin–Madison, 2Department of Electrical and Computer Engineering, University of Wisconsin–Madison, 3Graduate Program in Cellular and Molecular Biology, University of Wisconsin–Madison, 4The Genome Center, University of Wisconsin–Madison

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识别基因组靶向分子的直接目标仍然是一个重大的挑战。要了解DNA结合分子如何参与基因组，我们开发了依靠小分子交联，染色质隔离的方法（COSMIC）。

Tags

分子生物学，第107，COSMIC，CSI，分子识别，化学信息学，化学基因组学，聚酰胺，基因组定位，精密医学，DNA，染色质免疫沉淀，新一代测序
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