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Моделирование резистентностью к химиотерапии лейкоз<em> In Vitro</em
Journal JoVE
Médecine
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Journal JoVE Médecine
Modeling Chemotherapy Resistant Leukemia In Vitro
DOI:

08:41 min

February 09, 2016

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Chapitres

  • 00:05Titre
  • 00:37Co-culture Maintenance
  • 02:24Gel Type 10 Cross-linked Dextran (G10) Bead Column Preparation
  • 04:08Subpopulation Separation
  • 06:06G10 Column Leukemic Cell Collection
  • 07:26Results: PD Leukemic Cells Exhibit an Increased Resistance to Chemotherapy Exposure
  • 08:07Conclusion

Summary

Traduction automatique

The current report summarizes a protocol that can be utilized to model the influence of the bone marrow microenvironment niche on leukemic cells with emphasis placed on enrichment of the most chemoresistant subpopulation.

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