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En Rat carotis ballon Skade Model til Test Anti-vaskulære Remodeling Therapeutics
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Journal JoVE Médecine
A Rat Carotid Balloon Injury Model to Test Anti-vascular Remodeling Therapeutics

En Rat carotis ballon Skade Model til Test Anti-vaskulære Remodeling Therapeutics

DOI:
10.3791/53777-v

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08:42 min

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September 19, 2016

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, , , , ,
1Laboratory of Cardiovascular Sciences,National Institute on Aging, 2Department of Biomedical Science and Research Institute for Bioscience and Biotechnology,Hallym University

Chapitres

  • 00:05Titre
  • 01:08Surgical Preparation
  • 02:37Left Carotid Artery Dissection and Isolation
  • 06:25Results: Representative Rat Balloon Catheter Injury-induced Vascular Tissue Remodeling
  • 07:23Conclusion

Summary

Traduction automatique

Traduction automatique

The rat carotid balloon injury model described below allows researchers to evaluate drugs or therapeutics that negate injury-induced arterial hyperplasia. Detailed pre-surgical preparation, surgical procedure, and post-surgical cares of the animal are described.

Tags

Keywords: Rat CarotidBalloon InjuryVascular RemodelingAngioplastyNeointimal HyperplasiaCardiovascular ResearchSurgical InjuryTherapeutic ReagentsBalloon CatheterWistar RatCarotid ArteryVagus NerveBlunt Dissection

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