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Preparation and Characterization of Lipophilic Doxorubicin Pro-drug Micelles
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Journal JoVE Bio-ingénierie
Preparation and Characterization of Lipophilic Doxorubicin Pro-drug Micelles

Preparation and Characterization of Lipophilic Doxorubicin Pro-drug Micelles

DOI:
10.3791/54338-v

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09:56 min

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August 02, 2016

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, , , , ,
1School of Pharmacy,Hampton University

Chapitres

  • 00:05Titre
  • 01:00Synthesis of DOX-PA
  • 03:10Preparation of DOX-PA Micelles by Film-dispersion Method
  • 04:23Characterization of DOX-PA Micelles
  • 07:02Results: Characterization of DOX-PA and Micelles Formulations
  • 09:08Conclusion

Summary

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Traduction automatique

A protocol for the preparation and characterization of lipophilic doxorubicin pro-drug loaded 1,2-distearoyl-sn-glycero-3-phosphoethanolamine-N-[amino(polyethylene glycol)-2000] (DSPE-PEG) micelles is described.

Tags

Lipophilic Doxorubicin Pro-drugMicell FormulationsDrug LoadingDrug StabilityDrug TargetingNanomedicineDOX-PADSPE-PEGSilica Gel ColumnThin Layer ChromatographyDulbecco’s Phosphate Buffer

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