L'Assemblée et l'application des «Shear Anneaux»: A Novel Endothelial Modèle pour Orbital, unidirectionnel et périodique Fluid débit et contrainte de cisaillement

Different levels and patterns of fluid shear are known to modulate endothelial gene expression, phenotype and susceptibility to disease. We discuss the assembly and use of 'shear rings': a model that produces unidirectional, periodic shear stress patterns. Shear rings are simple to assemble, economical and can produce high cell yields.