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경색 지역의 중간 동맥 폐색 기술 및 시각화를 사용하여 마우스의 허혈성 뇌졸중 및 허혈 - 재관류 유도
Journal JoVE
Médecine
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Journal JoVE Médecine
Induction of Ischemic Stroke and Ischemia-reperfusion in Mice Using the Middle Artery Occlusion Technique and Visualization of Infarct Area
DOI:

09:08 min

February 02, 2017

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Chapitres

  • 00:05Titre
  • 00:37Dissection of the Common Carotid Artery and Internal/External Branching
  • 02:53Preparation of the CCA for the MCAO Suture Insertion
  • 03:51Middle Cerebral Artery Occlusion
  • 05:59Reperfusion
  • 07:07Results: Characteristics of Brain Tissue Following Ischemia-Reperfusion
  • 08:38Conclusion

Summary

Traduction automatique

We describe a mouse model of stroke induced by the occlusion of the middle cerebral artery using a silicone coated suture. The protocol can be applied to induce permanent occlusion or a temporary ischemia, followed by reperfusion.

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