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磷31磁共振波谱分析：一种测量工具<em>在体内</em>线粒体氧化磷酸化能力人骨骼肌
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Médecine
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Journal JoVE Médecine
Phosphorus-31 Magnetic Resonance Spectroscopy: A Tool for Measuring In Vivo Mitochondrial Oxidative Phosphorylation Capacity in Human Skeletal Muscle
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磷31磁共振波谱分析：一种测量工具<em>在体内</em>线粒体氧化磷酸化能力人骨骼肌

DOI:
10.3791/54977-v

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09:40 min

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January 19, 2017

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, , , , , ,
1Davis Heart and Lung Research Institute,The Ohio State University, 2Laboratory of Clinical Investigation,National Institute on Aging, 3Division of Endocrinology, Diabetes and Metabolism,The Ohio State University, 4Department of Human Sciences, Human Nutrition,The Ohio State University, 5Division of Endocrinology and Diabetes, Department of Pediatrics,University of Pennsylvania

Chapitres

  • 00:05Titre
  • 01:09Preparation and Subject Positioning
  • 03:25Scanning Protocol
  • 05:47Baseline Exercise and Post-exercise Acquisition
  • 07:08Results: Phosphors-31 Magnetic Resonance Spectroscopy
  • 08:24Conclusion

Summary

Traduction automatique

Traduction automatique

This work demonstrates the feasibility of an in vivo phosphorus-31 magnetic resonance spectroscopy (31PMRS) technique to quantify mitochondrial oxidative phosphorylation (OXPHOS) capacity in human skeletal muscle.

Tags

Keywords: Phosphorus-31 Magnetic Resonance SpectroscopyIn VivoMitochondrial Oxidative PhosphorylationSkeletal MuscleNoninvasive MeasurementExercise ProtocolTargeted TherapiesMRICoil PositioningSubject Positioning

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