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Continuous Manual Exchange Transfusion for Patients with Sickle Cell Disease: An Efficient Method to Avoid Iron Overload
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Médecine
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Journal JoVE Médecine
Continuous Manual Exchange Transfusion for Patients with Sickle Cell Disease: An Efficient Method to Avoid Iron Overload

Continuous Manual Exchange Transfusion for Patients with Sickle Cell Disease: An Efficient Method to Avoid Iron Overload

DOI:
10.3791/55172-v

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05:23 min

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March 14, 2017

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, , , , , , , ,
1Reference Centre of Sickle Cell Disease, Hematology Unit,Robert Debré Hospital, AP-HP, 2School of Pharmacy,Université Paris Descartes, 3Etablissement Français du Sang,Robert Debré Hospital, AP-HP, 4Hematology Unit,,Robert Debré Hospital, AP-HP, Univsité Paris Diderot

Chapitres

  • 00:05Titre
  • 00:54Patient and Blood Product Preparation
  • 02:20Optional Initial Isovolemic Phlebotomy
  • 03:25Isovolemic Exchange Transfusion and Final Laboratory Test
  • 04:13Results: Representative Iron Overloads during Manual Exchange Transfusion or Erythrapheresis Programs
  • 04:54Conclusion

Summary

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We have outlined a method of continuous manual exchange transfusion for the treatment of sickle cell disease in patients. This safe protocol was designed to effectively limit iron overload in patients in need of chronic transfusions and can be used extensively without any special equipment.

Tags

Keywords: Sickle Cell DiseaseContinuous Manual Exchange TransfusionIron OverloadPhlebotomyAlbuminPacked Red Blood CellsIsovolemicHemodynamic ParametersCalciumOxygen

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