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Bioluminescence and Near-infrared Imaging of Optic Neuritis and Brain Inflammation in the EAE Model of Multiple Sclerosis in Mice
 

Bioluminescence and Near-infrared Imaging of Optic Neuritis and Brain Inflammation in the EAE Model of Multiple Sclerosis in Mice

Article DOI: 10.3791/55321-v • 08:05 min • March 1st, 2017
March 1st, 2017 •
1, 1
1Institute of Clinical Pharmacology, University Hospital Frankfurt

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We show a technique for in vivo live bioluminescence and near-infrared imaging of optic neuritis and encephalitis in the experimental autoimmune encephalomyelitis (EAE) model for multiple sclerosis in SJL/J mice.

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Keywords: Bioluminescence Near-infrared Imaging Optic Neuritis Brain Inflammation EAE Model Multiple Sclerosis Mice Neuroimmunology Therapy PTX PLP/CFA CFA Clinical Symptoms In Vivo Imaging Isoflurane Anesthesia
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