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Synthesis of Biocompatible Liquid Crystal Elastomer Foams as Cell Scaffolds for 3D Spatial Cell Cultures
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Bio-ingénierie
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Journal JoVE Bio-ingénierie
Synthesis of Biocompatible Liquid Crystal Elastomer Foams as Cell Scaffolds for 3D Spatial Cell Cultures
DOI:

13:38 min

April 11, 2017

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Chapitres

  • 00:05Titre
  • 01:07Synthesis of α-Three-arm Star Block Copolymer (SBC-αCl)
  • 04:37Fabrication of a Porous 3D Liquid Crystal Elastomer (LCE) Scaffold with Hexamethylene Diisocyanate (HDI) as a Crosslinker
  • 07:27Seeding the LCE Scaffold Using Sterile Techniques and Imaging the LCE Construct
  • 10:15Results: 3D Spatial Cell Cultures Prepared on LCE Foams
  • 12:03Conclusion

Summary

Traduction automatique

This study presents a methodology to prepare 3D, biodegradable, foam-like cell scaffolds based on biocompatible side-chain liquid crystal elastomers (LCEs). Confocal microscopy experiments show that foam-like LCEs allow for cell attachment, proliferation, and the spontaneous alignment of C2C12s myoblasts.

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