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Journal / Bioengineering / 转换纳米粒子介导的激酶活化远程触发细胞内信号转导的集成系统…
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JoVE Journal Bioengineering
转换纳米粒子介导的激酶活化远程触发细胞内信号转导的集成系统
 
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转换纳米粒子介导的激酶活化远程触发细胞内信号转导的集成系统

Article DOI: 10.3791/55769-v • 11:20 min • August 30th, 2017
August 30th, 2017 •
1,2, 1, 1,2, 3, 1,2, 1
1Institute of Chemistry, Academia Sinica, 2Department of Chemistry, National Taiwan University, 3Department of Materials and Mineral Resources Engineering, National Taipei University of Technology

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在这个协议中, 笼状蛋白激酶 a (PKA), 细胞信号转导 bioeffector, 被固定在纳米粒子表面, 微量进入胞, 并激活由 upconverted 紫外线光近红外线 (近红外) 照射, 诱导下游应力纤维解体的胞。

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生物工程 问题 126 笼酶 细胞反应 显微注射 光解 蛋白激酶 A 转换纳米颗粒 活化
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