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Reproducible Motor Deficit Following Aortic Occlusion in a Rat Model Of Spinal Cord Ischemia
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Médecine
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Journal JoVE Médecine
Reproducible Motor Deficit Following Aortic Occlusion in a Rat Model Of Spinal Cord Ischemia

Reproducible Motor Deficit Following Aortic Occlusion in a Rat Model Of Spinal Cord Ischemia

DOI:
10.3791/55814-v

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08:10 min

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July 22, 2017

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, , , , , ,
1Department of Anesthesiology and Pain Medicine,SMG-SNU Boramae Medical Center, Seoul National University College of Medicine, Seoul, 2Department of Anesthesiology and Pain Medicine,SNU Bundang Hospital, Seongnamsi, Gyeonggido, Republic of Korea

Chapitres

  • 00:00Titre
  • 00:15Introduction
  • 01:07Prepare for Surgery
  • 01:44Femoral Artery Catheterization
  • 03:05Carotid Artery Catheterization
  • 04:06Tail Artery Catheterization
  • 05:03Induction of Spinal Cord Ischemia
  • 05:31Post-surgical Care
  • 06:10Representative Results
  • 07:41Conclusion

Summary

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This study demonstrates the technique to make a minimally invasive and easily reproducible model of spinal cord ischemia in rats. Various degrees of hind limb motor deficit can be produced by controlling the aortic occlusion time.

Tags

Spinal Cord IschemiaAortic OcclusionMotor DeficitFogarty CatheterHind-limb Motor FunctionMotor Deficit IndexRat ModelThoracoabdominal Aortic Aneurysm SurgeryExperimental Model

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