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Journal / Cancer Research / Induktion og diagnose af tumorer i
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JoVE Journal Cancer Research
Induktion og diagnose af tumorer i
 
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Induktion og diagnose af tumorer i

Article DOI: 10.3791/55901-v • 08:14 min • July 25th, 2017
July 25th, 2017 •
1,2, 1
1Structural Biology Center, National Institute of Genetics and Department of Genetics, School of Life Science, SOKENDAI, 2Graduate School of Media and Governance, Keio University

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Mosaik klonanalyse i Drosophila imaginal disc epithelia er et kraftfuldt model system til at studere tumoregenesens genetiske og cellulære mekanismer. Her beskriver vi en protokol til at fremkalde tumorer i Drosophila- vinge-imaginale diske ved hjælp af GAL4-UAS-systemet og indføre en diagnosemetode til klassificering af tumorfænotyperne.

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Cancerbiology Drosophila Imaginal disc Tumorigenesis Neoplasia Dysplasi Tumor suppressor gen GAL4-UAS RNAi
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