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3D Microtissues for Injectable Regenerative Therapy and High-throughput Drug Screening
Journal JoVE
Bio-ingénierie
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Journal JoVE Bio-ingénierie
3D Microtissues for Injectable Regenerative Therapy and High-throughput Drug Screening
DOI:

11:28 min

October 04, 2017

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Chapitres

  • 00:05Titre
  • 01:18Fabrication of 3D Microcryogels
  • 03:11Injectable 3D Microtissues for Treatment of Critical Limb Ischemia
  • 07:09Assembly of Microtissue Array Chip for High-throughput Drug Screening
  • 09:05Results: Microcryogels Used as a Therapeutic and for High-throughput Drug-screening
  • 10:31Conclusion

Summary

Traduction automatique

This protocol describes the fabrication of elastic 3D macroporous microcryogels by integrating microfabrication with cryogelation technology. Upon loading with cells, 3D microtissues are generated, which can be readily injected in vivo to facilitate regenerative therapy or assembled into arrays for in vitro high-throughput drug screening.

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