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JoVE Journal Neuroscience
Müller Glia celle aktivering i en Laser-induceret Retinal Degeneration og Regeneration Model i zebrafisk
 
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Müller Glia celle aktivering i en Laser-induceret Retinal Degeneration og Regeneration Model i zebrafisk

Article DOI: 10.3791/56249-v • 06:27 min • October 27th, 2017
October 27th, 2017 •
1,2,3, 1, 1,2,3, 1, 1,2
1Department of Ophthalmology, University Hospital of Bern, University of Bern, 2Department of Clinical Research, University of Bern, 3Graduate School for Cellular and Biomedical Sciences, University of Bern

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For zebrafisk er en populær animalsk model til at studere mekanismer af retinale degeneration eller regenerering i hvirveldyr. Denne protokol beskriver en metode til at fremkalde lokaliserede skade forstyrre den ydre retina med minimal skade på den indre nethinde. Efterfølgende, overvåger vi i vivo retinal morfologi og Müller glia svar i hele retinal regenerering.

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Neurobiologi spørgsmålet 128 cellebiologi zebrafisk laserbehandling nethinden degeneration regenerering Müller celler optisk kohærens tomografi
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