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An Efficient and Reproducible Protocol for Distraction Osteogenesis in a Rat Model Leading to a Functional Regenerated Femur
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Bio-ingénierie
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Journal JoVE Bio-ingénierie
An Efficient and Reproducible Protocol for Distraction Osteogenesis in a Rat Model Leading to a Functional Regenerated Femur

An Efficient and Reproducible Protocol for Distraction Osteogenesis in a Rat Model Leading to a Functional Regenerated Femur

DOI:
10.3791/56433-v

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09:26 min

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October 23, 2017

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, , , , , , ,
1CNRS, ISM, Inst Movement Sci,Aix Marseille Univ, 2Sainte-Marguerite Hospital, Institute for Locomotion, Department of Orthopaedics and Traumatology,APHM, 3Sainte-Marguerite Hospital, Institute for Locomotion, Department of Peadiatric Orthopaedics,APHM, 4Ecole centrale de Marseille, 5Faculté de Pharmacie,Laboratoire de Biochimie, 6Service Central de la Qualité et de l’Information Pharmaceutiques,APHM

Chapitres

  • 00:05Titre
  • 01:10Femur Explant Fixator Implantation and Osteotomization
  • 04:30Distraction and Femur Resection
  • 06:05Results: Representative Femur Regeneration Analyses
  • 08:06Conclusion

Summary

Traduction automatique

Traduction automatique

This study describes a reproducible and detailed protocol using a newly developed external fixator for distraction osteogenesis (DO) in a femoral rat model which permits physiological weight-bearing by the animal after removal of the external fixator.

Tags

Keywords: Distraction OsteogenesisRat ModelFemur RegenerationExternal FixatorBone LengtheningBone DefectBone RepairBone RegenerationReproducible ProtocolSurgical Procedure

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