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Immunology and Infection

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JoVE Journal Immunology and Infection
Stenosis of the Inferior Vena Cava
 

Stenosis of the Inferior Vena Cava: A Murine Model of Deep Vein Thrombosis

Article DOI: 10.3791/56697-v • 05:37 min • December 22nd, 2017
December 22nd, 2017 •
1, 1
1Institute of Cardiovascular Sciences, College of Medical and Dental Sciences, University of Birmingham

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We describe here stenosis in the inferior vena cava as a murine model of deep vein thrombosis. This model recapitulates blood flow restriction, one of the major triggers of venous thrombosis in humans.

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Keywords: Stenosis Inferior Vena Cava Murine Model Deep Vein Thrombosis Blood Flow Distortion Thrombosis Initiation Surgical Procedure Anesthetized Mouse Abdominal Incision Inferior Vena Cava Ligation Aorta Left Renal Vein Prolene Suture
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