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Surgical Techniques for Catheter Placement and 5/6 Nephrectomy in Murine Models of Peritoneal Dialysis
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Ingénierie
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Journal JoVE Ingénierie
Surgical Techniques for Catheter Placement and 5/6 Nephrectomy in Murine Models of Peritoneal Dialysis

Surgical Techniques for Catheter Placement and 5/6 Nephrectomy in Murine Models of Peritoneal Dialysis

DOI:
10.3791/56746-v

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07:11 min

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July 19, 2018

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, , , ,
1Molecular Biology Research Centre Severo Ochoa,Spanish National Research Council, 2IdiPAZ Research Institute,La Paz University Hospital, 3Princesa Research Institute,La Princesa University Hospital

Chapitres

  • 00:04Titre
  • 01:03Catheter Placement
  • 03:335/6 Nephrectomy and Catheter Placement
  • 05:34Results: Representative Peritoneal Dialysis Effects
  • 06:28Conclusion

Summary

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This article shows the method for the surgical placement in mice of an intraperitoneal catheter attached to an access port that is positioned at the back of the animal. Moreover, it explains the procedure for a 5/6 nephrectomy to resemble the uremic state of PD patients.

Tags

Keywords: Catheter PlacementNephrectomyMurine ModelsPeritoneal DialysisUremic ConditionsGenetically Modified AnimalsPeritoneal DamageMolecular CuesSurgical TechniquePeritoneal CavityPeritoneal WallPeritoneal Dialysis Fluid

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