Waiting
Traitement de la connexion…

Trial ends in Request Full Access Tell Your Colleague About Jove
Journal / Biochemistry / Fånga interaktion kineticsen av en jonkanal…
JoVE Journal
Biochemistry

Un abonnement à JoVE est nécessaire pour afficher ce contenu. Connectez-vous ou commencez votre essai gratuit.

JoVE Journal Biochemistry
Fånga interaktion kineticsen av en jonkanal Protein med små molekyler av Bio-lager interferometri analysen
 
Click here for the English version

Fånga interaktion kineticsen av en jonkanal Protein med små molekyler av Bio-lager interferometri analysen

Article DOI: 10.3791/56846-v • 10:41 min • March 7th, 2018
March 7th, 2018 •
1, 2, 1, 3
1Department of General Surgery, Tongren Hospital, Shanghai Jiao Tong University School of Medicine, 2Key Laboratory of Systems Biomedicine (Ministry of Education), Institute of Systems Biomedicine, Shanghai Jiao Tong University, 3Hongqiao International Institute of Medicine, Tongren Hospital, Shanghai Jiao Tong University School of Medicine

Chapitres

résumé
Automatic Translation

Please note that all translations are automatically generated.

Click here for the English version.

Protokollet här beskriver samspelet mellan renat hEAG1 ion kanal protein med liten molekyl lipid ligand fosfatidylinositol 4, 5-bisphosphate (PIP2). Mätningen visar att BLI kunde vara en potentiell metod för romanen småmolekylär ion kanal ligand screening.

Tags

Biokemi fråga 133 Bio-lager Interferometry (BLI) ion kanal protein liten molekyl protein affinitet rening däggdjur stabilt uttryck systemet mänskliga EAG1 (hEAG1) kanal läkemedelsutveckling terapeutiska mål ligand screening
Read Article

Get cutting-edge science videos from JoVE sent straight to your inbox every month.

Waiting X
Simple Hit Counter