/

/

微电极阵列技术在完整仔猪脑麻醉诱导神经毒性研究中的应用

Journal JoVE
Neurosciences

This content is Free Access.

Journal JoVE Neurosciences

Adaptation of Microelectrode Array Technology for the Study of Anesthesia-induced Neurotoxicity in the Intact Piglet Brain

Please note that all translations are automatically generated. Click here for the English version.

微电极阵列技术在完整仔猪脑麻醉诱导神经毒性研究中的应用

DOI:

10.3791/57391-v

•

08:23 min

•

May 12, 2018

•

Emily D. Geyer*¹, Prithvi A. Shetty*¹, Christopher J. Suozzi*¹, David Z. Allen*^1,2, Pamela P. Benavidez*^1,2, Joseph Liu*^1,3, Charles N. Hollis, Greg A. Gerhardt, Jorge E. Quintero, Jason J. Burmeister, Emmett E. Whitaker³

¹Department of Anesthesiology,Ohio State University College of Medicine, ²Medical Student Research Program,Ohio State University College of Medicine, ³Department of Anesthesiology and Pain Medicine,Nationwide Children’s Hospital, ⁴Department of Neuroscience,University of Kentucky Medical Center

Chapitres

00:04Titre
01:19Set Up for Surgery
03:38Microelectrode Array Placement
06:19Results: In Vivo Glutamate Measurements from the Piglet Hippocampus
07:56Conclusion

Summary

Traduction automatique

本研究探讨了用酶基微电极阵列技术监测仔猪体内的活体神经递质活性的新方法.假设谷氨酸失调有助于麻醉神经毒性的机制。在此, 我们提出了一种适应多边环境技术的协议, 研究麻醉诱发神经毒性的机制。

Tags

Microelectrode Array Neurotransmitters Anesthesia-induced Neurotoxicity Piglet Brain In Vivo Glutamate Activity Pediatric Brain Trauma Epilepsy Stroke Piglet Model Sevoflurane Anesthesia Stereotaxic Frame Rocuronium Vital Signs Monitoring

Article

Embed

AJOUTER À LA PLAYLIST

Usage Statistics

Vidéos Connexes

可伸缩流控喷油器阵列病毒完整的3 - D的大脑回路为目标

高密度的自由移动，使用基于聚酰亚胺的微电极的小鼠的脑电图记录

可视化本体感受器<em>果蝇</em>幼虫和蛹

鉴定转基因鱼的完整的大脑中的神经元的电活动记录

在完整的成年斑马鱼大脑电生理记录

小脑颗粒神经元的遗传操作<em>体外</em>和<em>在体内</em>为研究神经元形态和迁移

嗅觉系统作为模型来研究轴突生长的模式和形态<em>在体内</em

微电极引导电极植入到大鼠丘脑底核的长期深部脑刺激

小容积回收-灌注-浸没式室系统中维持的急性海马切片的突触可塑性记录

常见马莫塞的全皮质电皮质阵列的慢性植入

Read Article