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Immunology and Infection

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JoVE Journal Immunology and Infection
Evaluering av Zika Virus-spesifikke T-celle svar i Immunoprivileged organer av infiserte Ifnar1- / - mus
 
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Evaluering av Zika Virus-spesifikke T-celle svar i Immunoprivileged organer av infiserte Ifnar1- / - mus

Article DOI: 10.3791/58110-v • 10:01 min • October 17th, 2018
October 17th, 2018 •
*1,2, *2, *3, 1,2, 4, 2, 5, 6, 3, 1,2,4,6, 1,2
1School of Laboratory Medicine and Life Sciences, Wenzhou Medical University, 2NHC Key Laboratory of Medical Virology and Viral Diseases, National Institute for Viral Disease Control and Prevention, Chinese Center for Disease Control and Prevention, 3State Key Laboratory of Agrobiotechnology, College of Biological Sciences, China Agricultural University, 4Research Network of Immunity and Health (RNIH), Beijing Institutes of Life Science, Chinese Academy of Sciences, 5Laboratory Animal Center, Chinese Center for Disease Control and Prevention, 6CAS Key Laboratory of Pathogenic Microbiology and Immunology, Institute of Microbiology, Chinese Academy of Sciences
* These authors contributed equally

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En protokoll for å evaluere antigen-spesifikke T-celle svar i immunoprivileged organer i Ifnar1- / - murine modellen for Zika virusinfeksjonen (ZIKV) er beskrevet. Denne metoden er avgjørende for å undersøke mobilnettet mekanismer for beskyttelse og immunopathogenesis av ZIKV vaksiner og er også verdifull for deres effekt evaluering.

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Immunologi og infeksjon problemet 140 Zika virus antigen-spesifikke T celle vaksinasjon immunoprivileged organer tetramer
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