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Fabrikation af anisotrope polymere kunstige Antigen præsentere celler for CD8 + T-celle aktivering
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1Biomedical Engineering, Translational Tissue Engineering Center, Institute for Nanobiotechnology,Johns Hopkins University School of Medicine, 2Biomedical Engineering, Translational Tissue Engineering Center, Institute for Nanobiotechnology, Ophthalmology, Oncology, Neurosurgery, Materials Science and Engineering, Chemical and Biomolecular Engineering, and the Bloomberg-Kimmel Institute for Cancer Immunotherapy,Johns Hopkins University School of Medicine
Chapitres
- 00:04Titre
- 00:49Tunable Spherical Poly(Lactic-Co-Glycolic Acid) (PLGA) Fabrication
- 03:30Tunable Polymeric Particle Fabrication
- 06:21Surface Protein Conjugation for Artificial Antigen Presenting Cell (aAPC) Creation
- 08:01Results: Representative Spherical and Ellipsoidal Particle Characterization
- 09:49Conclusion
Vi præsenterer her, en protokol for at hurtigt og reproducerbar generere biologisk inspirerede, biologisk nedbrydelige articifical antigen præsentere celler (aAPC) med afstemmelige størrelse, form og overflade protein præsentation for T-celle ekspansion ex vivo eller in vivo .
