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Analysis of Cancer Cell Invasion and Anti-metastatic Drug Screening Using Hydrogel Micro-chamber Array (HMCA)-based Plates
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Chapitres
- 00:04Titre
- 01:17Hyrdogel Micro-chamber Array (HMCA) Plate Embossing
- 02:28Cell Loading and Spheroid Formation
- 04:26Invasion Assay Acquisition and Analysis
- 06:06Results: Representative Influence of Extracellular Matrix (ECM) Composition on Spheroid Invasion
- 07:25Conclusion
A HMCA-based imaging plate is presented for invasion assay performance. This plate facilitates the formation of three-dimensional (3D) tumor spheroids and the measurement of cancer cell invasion into the extracellular matrix (ECM). The invasion assay quantification is achieved by semi-automatic analysis.
