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Left Atrial Stenosis Induced Pulmonary Venous Arterialization and Group 2 Pulmonary Hypertension in Rat
Journal JoVE
Médecine
Author Produced
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Journal JoVE Médecine
Left Atrial Stenosis Induced Pulmonary Venous Arterialization and Group 2 Pulmonary Hypertension in Rat
DOI:

08:34 min

November 18, 2018

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Chapitres

  • 00:00Titre
  • 01:20Pre-operative Preparation
  • 02:02Anaesthesia and Endotracheal Intubation
  • 03:11Preparation of the Surgical Site
  • 03:38Left Atrial Stenosis Surgery
  • 06:11Confirm the Success of Left Atrial Stenosis with Echocardiography
  • 06:21Representative Results
  • 07:43Conclusion

Summary

Traduction automatique

Left atrial stenosis (LAS) is a novel surgical technique used for studying group 2 pulmonary hypertension (PH) and mechanisms underlying pulmonary venous arterialization. Here, we present a protocol to constrict the left atrium using a titanium clip to cause pulmonary venous arterialization and moderate PH in a rat.

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