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1Department of Chemistry,Brooklyn College, The City University of New York, 2Ph.D. Program in Chemistry,The Graduate Center of The City University of New York, 3Ph.D. Program in Biochemistry,The Graduate Center of The City University of New York, 4Department of Genetics and Genomic Sciences,Icahn School of Medicine at Mount Sinai, 5Women’s Health Research Institute,Icahn School of Medicine at Mount Sinai, 6Laboratory for Translational Research,Western Connecticut Health Network
Chapitres
- 00:04Titre
- 00:35Synthesis of Oleic Acid-Platinum(II) Conjugate
- 02:41Preparation of Unmodified and Fluorescein Isothiocyanate (FITC)-Modified Lysine-Tyrosine-Phenylalanine (KYF) Tripeptide
- 05:59Synthesis of FITC-KYF-Stabilized or KYF-Stabilized Nanoemulsion with Oleic Acid-Pt(II) Cores (FITC-KYF-Pt-NE or KYF-Pt-NE)
- 08:03Results: KYF-Pt-NE and FITC-KYF-Pt-NE Characterization
- 09:43Conclusion
Este protocolo describe un método eficiente para sintetizar una nanoemulsión de un conjugado de ácido oleico acids-platinum(II) estabilizado con un tripéptido de lisina-tirosina-fenilalanina (KYF). Las formas de nanoemulsión condiciones suaves sintético a través de autoensamblaje de lo KYF y el conjugado.
