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Morphological and Functional Evaluation of Ribbon Synapses at Specific Frequency Regions of the Mouse Cochlea
Journal JoVE
Neurosciences
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Journal JoVE Neurosciences
Morphological and Functional Evaluation of Ribbon Synapses at Specific Frequency Regions of the Mouse Cochlea
DOI:

09:54 min

May 10, 2019

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Chapitres

  • 00:04Titre
  • 00:50Animal Selection
  • 02:12Cochlear Tissue Processing
  • 04:08Immunofluorescence Staining
  • 05:53Morphological Cochlear Ribbon Synapse Evaluation
  • 07:37Results: Representative Cochlear Frequency Localization and Cochlear Ribbon Analysis
  • 09:08Conclusion

Summary

Traduction automatique

This manuscript describes an experimental protocol for evaluating the morphological characteristics and functional status of ribbon synapses in normal mice. The present model is also suitable for noise-induced and age-related cochlear synaptopathy-restricted models. The correlative results of previous mouse studies are also discussed.

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