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Three-Dimensional Bone Extracellular Matrix Model for Osteosarcoma
Journal JoVE
Recherche en cancérologie
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Journal JoVE Recherche en cancérologie
Three-Dimensional Bone Extracellular Matrix Model for Osteosarcoma
DOI:

08:07 min

April 12, 2019

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Chapitres

  • 00:04Titre
  • 00:59Bone Preparation and Demineralization
  • 02:29Bone Decellularization
  • 04:08Cell Seeding and Culture
  • 06:26Results: Characterization of Decellularized BEM and OS Cells
  • 07:44Conclusion

Summary

Traduction automatique

The bone extracellular matrix (BEM) model for osteosarcoma (OS) is well established and shown here. It can be used as a suitable scaffold for mimicking primary tumor growth in vitro and providing an ideal model for studying the histologic and cytogenic heterogeneity of OS.

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