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Assessing Therapeutic Angiogenesis in a Murine Model of Hindlimb Ischemia
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Médecine
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Journal JoVE Médecine
Assessing Therapeutic Angiogenesis in a Murine Model of Hindlimb Ischemia

Assessing Therapeutic Angiogenesis in a Murine Model of Hindlimb Ischemia

DOI:
10.3791/59582-v

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07:48 min

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June 08, 2019

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, , , , , ,
1Centro Cardiovascular da Universidade de Lisboa,Lisbon School of Medicine of the Universidade de Lisboa, 2Centro Hospitalar Universitário Lisboa Norte, 3Nova Medical School/Faculdade de Ciências Médicas,Universidade Nova de Lisboa

Chapitres

  • 00:04Titre
  • 01:07Hindlimb Ischemia Induction
  • 03:06Gastrocnemius Muscle Harvest
  • 04:10Capillary Microdissection Laser Capture
  • 05:56Results: Representative Effects of Low-Dose Ionizing Radiation (LDIR) After Ischemia Induction
  • 07:12Conclusion

Summary

Traduction automatique

Traduction automatique

Here, a critical hindlimb ischemia experimental model is presented followed by a battery of functional, histologic and molecular tests to assess the effectiveness of angiogenic therapies.​

Tags

Hindlimb IschemiaTherapeutic AngiogenesisRevascularizationC57 Black Six Female MouseNeurovascular BundleExternal Iliac ArteryFemoral ArteryFemoral VeinPolypropylene SuturesGastrocnemius MusclesAchilles TendonBiceps Femoris

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