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Et humant perifert blod mononukleære celle (PBMC) Enpodet humaniseret xenograft model for translational immuno-onkologi (I-O) forskning
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Chapitres
- 00:04Titre
- 00:46Cyclophosphamide Myeloablation and Human Peripheral Blood Mononuclear Cell (PBMC) Transplantation and Tumor Engraftment
- 02:08Immunohistochemistry (IHC)
- 04:33In Vivo Efficacy and Pharmacodynamics Analyses
- 06:08Results: Representative PBMC- and Tumor-Engraftment and Anti-Tumor Antibody Treatment Analysis
- 07:16Conclusion
Vi beskriver et humant perifert blod mononukleære celle (PBMC)-baseret humaniseret xenograft musemodel for Translationel immuno-onkologiske forskning. Denne protokol kan tjene som en generel retningslinje for fastlæggelse og karakterisering af lignende modeller for I-O-terapi vurdering.
