Un abonnement à JoVE est nécessaire pour voir ce contenu. Connectez-vous ou commencez votre essai gratuit.
1Department of General Surgery, The First Affiliated Hospital,Xi’an Jiaotong University, 2Institute of Medical Research,Northwestern Polytechnical University, 3School of Life Sciences,Northwestern Polytechnical University, 4Department of Medicine,Xi’an Jiaotong University, 5Princess Margaret Cancer Center,University of Health Network, 6Department of Pathology,Nanjing Medical University
Chapitres
- 00:00Titre
- 01:11Mice Appendectomy
- 05:11Induction of Colitis-associated Colorectal Cancer with Azoxymethane (AOM) and Dextran Sodium Sulfate (DSS)
- 06:36Résultats
- 07:57Conclusion
Det presenterade protokollet beskriver en facile kirurgiskt avlägsnande av appendix (caecal patch) i en mus följt av induktion av inflammatorisk tarmsjukdom-associerad kolorektal cancer. Denna murina blindtarmsoperation modell möjliggör utredning av den biologiska roll Appendix i patogenesen av mänskliga gastrointestinala sjukdomar.
