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Cancer Research

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JoVE Journal Cancer Research
Anvendelse af menneskeskabte pluripotente stamceller til generering af tumor antigen-specifikke T-celler
 
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Anvendelse af menneskeskabte pluripotente stamceller til generering af tumor antigen-specifikke T-celler

Article DOI: 10.3791/59997-v • 10:57 min • October 24th, 2019
October 24th, 2019 •
*1,2, *1,2, 1,2, 1,2, 1, 3, 1,2
1Surgery Branch, National Cancer Institute, NIH, 2Center for Cell-Based Therapy, National Cancer Institute, NIH, 3Laboratory of Immunology, Institute for Frontier Life and Medical Sciences, Kyoto University
* These authors contributed equally

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Denne artikel beskriver en metode til at generere funktionelle tumor antigen-specifikke induceret pluripotente stamcelle-afledte CD8αβ+ enkelt positive T-celler ved hjælp af OP9/filen dll1 Co-kultur system.

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Kræftforskning pluripotente stamcelle induceret pluripotente stamcelle immunologi adoptiv celle overførsel T Celledifferentiering tumor antigen specificitet
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