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1Department of Surgery, Division of Vascular Surgery,University of North Carolina at Chapel Hill, 2Center for Nanotechnology in Drug Delivery,University of North Carolina at Chapel Hill, 3Curriculum in Toxicology & Environmental Medicine,University of North Carolina at Chapel Hill, 4Department of Cell Biology & Physiology,University of North Carolina at Chapel Hill, 5McAllister Heart Institute,University of North Carolina at Chapel Hill
Chapitres
- 00:05Introduction
- 00:47Common Carotid Artery (CCA) Identification
- 02:16CCA Dissection
- 03:29Carotid Artery Pressure-Controlled Segmental Balloon Injury
- 05:36Results: Representative Hematoxylin & Eosin (H&E) and Light Sheet Fluorescence Microscopy Imaging
- 06:19Conclusion
Den rotte halspulsåren ballon skade efterligner den kliniske angioplastik procedure, der udføres for at genoprette blodgennemstrømningen i aterosklerotiske fartøjer. Denne model fremkalder arteriel skade respons ved distending arteriel væg, og benægte intimal lag af endotelceller, i sidste ende forårsager remodeling og en intimal hyperplastisk reaktion.
