Journal
/
Biologie
/
Production of Near-Infrared Sensitive, Core-Shell Vaccine Delivery Platform
Journal JoVE
Biologie
Un abonnement à JoVE est nécessaire pour voir ce contenu.  Connectez-vous ou commencez votre essai gratuit.
Journal JoVE Biologie
Production of Near-Infrared Sensitive, Core-Shell Vaccine Delivery Platform

Production of Near-Infrared Sensitive, Core-Shell Vaccine Delivery Platform

DOI:
10.3791/60569-v

•

06:27 min

•

October 20, 2020

•

, ,
1Department of Biomedical Engineering,Texas A&M University

Chapitres

  • 00:04Introduction
  • 00:33Polybubble Formation
  • 01:55Cargo Centering
  • 02:40Small Molecule Cargo Release and Near Infrared (NIR) Polybubble Activation
  • 04:25Results: Representative NIR Sensitive, Core-Shell Vaccine Delivery Platform Fabrication
  • 05:57Conclusion

Summary

Traduction automatique

Traduction automatique

This article describes the protocols used to produce a novel vaccine delivery platform, "polybubbles," to enable delayed burst release. Polyesters including poly(lactic-co-glycolic acid) and polycaprolactone were used to form the polybubbles and small molecules and antigen were used as cargo.

Tags

Keywords: Near-infraredVaccine DeliveryPolybubbleCargo StabilityPCLPLGADAPhotopolymerizationCargo EncapsulationSmall Molecule ReleaseConfocal Microscopy

Article

Embed

AJOUTER À LA PLAYLIST

Usage Statistics

Vidéos Connexes

check_url/fr/60569?article_type=v

Technical Demonstration of Whole Genome Array Comparative Genomic Hybridization
check_url/fr/60569?article_type=v

Exploring Cognitive Functions in Babies, Children & Adults with Near Infrared Spectroscopy
check_url/fr/60569?article_type=v

Lentivirus Production
check_url/fr/60569?article_type=v

A Convenient and General Expression Platform for the Production of Secreted Proteins from Human Cells
check_url/fr/60569?article_type=v

The MultiBac Protein Complex Production Platform at the EMBL
check_url/fr/60569?article_type=v

A Strategy for Sensitive, Large Scale Quantitative Metabolomics
check_url/fr/60569?article_type=v

Phosphopeptide Analysis of Rodent Epididymal Spermatozoa
check_url/fr/60569?article_type=v

gDNA Enrichment by a Transposase-based Technology for NGS Analysis of the Whole Sequence of BRCA1, BRCA2, and 9 Genes Involved in DNA Damage Repair
check_url/fr/60569?article_type=v

Method for the Assessment of Effects of a Range of Wavelengths and Intensities of Red/near-infrared Light Therapy on Oxidative Stress In Vitro
check_url/fr/60569?article_type=v

Near Infrared (NIr) Light Increases Expression of a Marker of Mitochondrial Function in the Mouse Vestibular Sensory Epithelium

Read Article