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建模年龄相关的神经退行性疾病在 卡诺哈布迪蒂斯埃利根
Journal JoVE
Biologie
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Journal JoVE Biologie
Modeling Age-Associated Neurodegenerative Diseases in Caenorhabditis elegans
DOI:

07:04 min

August 15, 2020

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Chapitres

  • 00:00Introduction
  • 00:39Necrotic Cell Death-induced by Hyperactive Ion Channels
  • 04:06Protein Aggregate-induced Neurodegeneration
  • 05:58Representative Results: Monitor Necrotic Cell Death-Induced by Hyperactive Ion Channels and Protein Aggregate-induced Neurodegeneration
  • 06:30Conclusion

Summary

Traduction automatique

在这里,我们介绍和描述广泛的方法,利用一些多功能线虫模型,包括高活性离子通道诱导坏死和蛋白质聚合诱导神经毒性,以监测和解剖年龄相关的神经退行性疾病的细胞和分子基础。

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