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Bio-ingénierie
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Biofunctionalization of Magnetic Nanomaterials
Journal JoVE
Bio-ingénierie
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Journal JoVE Bio-ingénierie
Biofunctionalization of Magnetic Nanomaterials

Biofunctionalization of Magnetic Nanomaterials

DOI:
10.3791/61360-v

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06:40 min

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July 16, 2020

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, ,
1Division of Biological and Environmental Sciences and Engineering,King Abdullah University of Science and Technology, 2Division of Computer, Electrical and Mathematical Sciences and Engineering,King Abdullah University of Science and Technology

Chapitres

  • 00:04Introduction
  • 00:42Release of Iron Nanowires
  • 01:56Coating the Nanowires with APTES
  • 02:50Biofunctionalization of the Nanowires
  • 04:12Results: Analysis of Coated and Biofunctionalized Nanowires
  • 06:01Conclusion

Summary

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In this work, we provide a protocol to biofunctionalize magnetic nanomaterials with antibodies for specific cell targeting. As examples, we utilize iron nanowires to target cancer cells.

Tags

BiofunctionalizationMagnetic NanomaterialsIron-iron Oxide NanomaterialsMulti-segmented NanomaterialsIron-gold NanowiresCovalent BondAntibodiesAluminum DiscsSodium HydroxideNanowiresEthanolAPTESSonicationEDCSulfo-NHSMESAnti-CD44 AntibodyPBS

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