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1Division of Neonatology, Stead Family Department of Pediatrics,University of Iowa, 2Division of Maternal Fetal Medicine, Department of Obstetrics & Gynecology,University of Iowa, 3Division of Neonatology, Department of Pediatrics,Vanderbilt University, 4Department of Microbiology & Immunology,University of Iowa
Chapitres
- 00:04Introduction
- 00:52Establishment of FEMI in Pregnant Mice
- 02:06Delivery and Care of Offspring and Intestinal Harvesting
- 03:03Intestinal Injury Scoring
- 04:11Quantification of Paneth and Goblet Cells
- 06:35Results: Intestinal Injury of Newborn Mice Induced by FEMI
- 08:22Conclusion
Vi udviklede en model af chorioamnionitis at simulere fostereksponering for moderens inflammation (FEMI) uden komplikationer af levende organismer til at undersøge virkningerne af FEMI på udviklingen af afkom tarmkanalen. Dette giver mulighed for undersøgelse af mekanistiske årsager til udvikling af tarmskade efter chorioamnionitis.
