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A Novel Inhalation Mask System to Deliver High Concentrations of Nitric Oxide Gas in Spontaneously Breathing Subjects
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Médecine
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Journal JoVE Médecine
A Novel Inhalation Mask System to Deliver High Concentrations of Nitric Oxide Gas in Spontaneously Breathing Subjects

A Novel Inhalation Mask System to Deliver High Concentrations of Nitric Oxide Gas in Spontaneously Breathing Subjects

DOI:
10.3791/61769-v

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05:46 min

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May 04, 2021

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, , , , , , , , , ,
1Department of Anesthesia, Critical Care and Pain Medicine,Massachusetts General Hospital and Harvard Medical School, 2Division of Pediatric Critical Care Medicine, Department of Pediatrics,Massachusetts General Hospital and Harvard Medical School, 3Respiratory Care,Massachusetts General Hospital

Chapitres

  • 00:05Introduction
  • 01:00Patient Interface and Y-Piece Preparation
  • 02:06Scavenging Chamber Preparation
  • 02:42Nitric Oxide (NO) Reservoir and Medical Air Supply System Preparation
  • 03:55NO Delivery in Spontaneously Breathing Subjects
  • 04:30Results: Representative NO and NO2 Concentration Tracings During a 160 ppm NO Inhalation in a Healthy Healthcare Worker
  • 05:17Conclusion

Summary

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This simple and highly adaptable system device for the inhalation of high-concentration nitric oxide (NO) gas does not require mechanical ventilators, positive pressure, or high gas flows. Standard medical consumables and a snug-fitting mask are used to safely deliver NO gas to spontaneously breathing subjects.

Tags

Keywords: Nitric OxideInhalation MaskHigh-dose Nitric OxideCOVID-19Lung ColonizationCystic FibrosisPatient InterfaceOne-way ValvesY-piece ConnectorScavenging ChamberCalcium HydroxideOxygen SourceNitric Oxide Reservoir SystemAerosol T-pieceVentilator Elbow Connector

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