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Maximum Isometric Tetanic Force Measurement of the Tibialis Anterior Muscle in the Rat
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Neurosciences
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Journal JoVE Neurosciences
Maximum Isometric Tetanic Force Measurement of the Tibialis Anterior Muscle in the Rat

Maximum Isometric Tetanic Force Measurement of the Tibialis Anterior Muscle in the Rat

DOI:
10.3791/61926-v

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12:39 min

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June 26, 2021

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, , , , ,
1Department of Orthopedic Surgery,Mayo Clinic, 2Radboud University Medical Center, Radboud Institute for Health Sciences, Department of Plastic Surgery, Nijmegen, The Netherlands

Chapitres

  • 00:00Introduction
  • 01:09Calibration of Force Transducer
  • 02:39Pre-surgical Preparation
  • 03:14Surgical Approach to Common Peroneal Nerve
  • 04:37Dissection of Tibialis Anterior Muscle Tendon
  • 05:46Optimization of Muscle Length
  • 10:21Measurement of Isometric Tetanic Force
  • 12:04Conclusion

Summary

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Evaluation of motor recovery remains the benchmark outcome measure in experimental peripheral nerve studies. The isometric tetanic force measurement of the tibialis anterior muscle in the rat is an invaluable tool to assess functional outcomes after reconstruction of sciatic nerve defects. The methods and nuances are detailed in this article.

Tags

Isometric Tetanic ForceTibialis Anterior MuscleRatSciatic Nerve InjuryNerve ReconstructionNerve Defect ModelNerve AllograftNerve ConduitMotor Function RecoveryCommon Peroneal NerveForce TransducerCalibrationAnesthesiaHindlimb

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