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Journal
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Médecine
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A Reproducible Intensive Care Unit-Oriented Endotoxin Model in Rats
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Médecine
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Journal JoVE
Médecine
A Reproducible Intensive Care Unit-Oriented Endotoxin Model in Rats
A Reproducible Intensive Care Unit-Oriented Endotoxin Model in Rats
DOI:
10.3791/62024-v
•
05:56 min
•
February 20, 2021
•
Jan Heil
,
Martin Schläpfer
2
1
Institute of Physiology
,
University of Zurich
,
2
Institute of Anesthesiology
,
University Hospital of Zurich
Chapitres
00:05
Introduction
01:06
Anesthesia Induction, Animal Monitoring, Intravenous Access and Tracheostomy
03:06
Arterial Access, Baseline Measurement, Sepsis Induction and Follow-Up Measurements
04:37
Results: The Analysis of the Arterial Pressure, Sepsis and the Inflammatory Reaction in LPS-Treated and Non-Treated Animals
05:11
Conclusion
Summary
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Here, we present a reproducible intensive care unit-oriented endotoxin model in rats.
Tags
Intensive Care Unit
Endotoxemia
Sepsis Research
Animal Model
Arterial Catheter
Venous Catheter
Tracheostomy
Fluid Replacement
Vasoconstrictor
Anesthesia
Monitoring
Surgical Techniques
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