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En Murine Ommaya Xenograft-modell for å studere direkte målrettet terapi av leptomeningeal sykdom
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1Department of Neuro-Oncology,H. Lee Moffitt Cancer Center & Research Institute, 2Department of Tumor Biology,H. Lee Moffitt Cancer Center & Research Institute, 3Department of Comparative Medicine,University of South Florida, 4Department of Breast Oncology,H. Lee Moffitt Cancer Center & Research Institute, 5Department of Cancer Physiology,H. Lee Moffitt Cancer Center & Research Institute, 6Department of Drug Discovery,H. Lee Moffitt Cancer Center & Research Institute, 7Department of Medical Oncology,Roswell Park Comprehensive Cancer Center
Chapitres
- 00:04Introduction
- 01:07Injection of CTCs into CSF to Generate a Mouse LMD Model
- 03:37Murine Ommaya Assembly and Implantation
- 05:20Results: Direct-Targeted Immunotherapy Using the Murine Ommaya Increases the Overall Survival of Breast Cancer-Associated Leptomeningeal Disease Mice
- 06:37Conclusion
