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Multi-timescale mikroskopi metoder til karakterisering af fluorescerende-mærket Microbubbles for Ultralyd-udløst Drug Release
This content is Free Access.
1Physics of Fluids group, Department of Science and Technology, MESA+ Institute for Nanotechnology and Technical Medical (TechMed) Center,University of Twente, 2BIOS Lab-on-a-Chip group, Max Planck Center Twente for Complex Fluid Dynamics, MESA+ Institute for Nanotechnology and Technical Medical (TechMed) Center,University of Twente, 3Department of Biotechnology and Nanomedicine,SINTEF Industry, 4Department of Circulation and Medical Imaging,Norwegian University of Science and Technology, 5Department of Health Research,SINTEF Digital, 6Cancer Clinic,St. Olav’s Hospital, 7Department of Physics,Norwegian University of Science and Technology
Chapitres
- 00:05Introduction
- 00:45Imaging by Brightfield Microscopy
- 02:05Imaging by Fluorescence Microscopy
- 02:52Imaging Protocol by Intravital Microscopy
- 04:07Results: In Vitro and In Vivo Behavior of Insonified Microbubble
- 05:22Conclusion
De præsenterede protokoller kan bruges til at karakterisere reaktionen af fluorescerende-mærket mikrobobler designet til ultralyd-udløste lægemiddellevering applikationer, herunder deres aktiveringsmekanismer samt deres biovirkninger. Dette papir dækker en række in vitro - og in vivomikroskopiteknikker , der udføres for at fange de relevante længder og tidshorisonter.
