Journal
/
/
Optogenetisk fasövergång av TDP-43 i spinalmotoriska nervceller av zebrafisk larver
Journal JoVE
Neurosciences
Un abonnement à JoVE est nécessaire pour voir ce contenu.  Connectez-vous ou commencez votre essai gratuit.
Journal JoVE Neurosciences
Optogenetic Phase Transition of TDP-43 in Spinal Motor Neurons of Zebrafish Larvae
DOI:

07:14 min

February 25, 2022

, ,

Chapitres

  • 00:04Introduction
  • 01:36Preparation of Light Emitting Diode (LED) for Blue Light Illumination
  • 02:13Imaging of Zebrafish Larvae Expressing Optogenetic TAR DNA-binding Protein 43 (TDP-43)
  • 03:58Light Stimulation of Optogenetic TDP-43h-Expressing Fish by Field Illumination of a Blue LED Light
  • 04:35Results: Characterization of TDP-43 Phase Transition in Spinal Motor Neurons of Zebrafish Larvae
  • 06:34Conclusion

Summary

Traduction automatique

Vi beskriver ett protokoll för att inducera fas övergång av TAR DNA-bindande protein 43 (TDP-43) med ljus i spinal motor nervceller med zebrafisk som modell.

Vidéos Connexes

Read Article