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Evaluation of Hepatic Glucose Production in a Polycystic Ovary Syndrome Mouse Model
Journal JoVE
Médecine
Author Produced
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Journal JoVE Médecine
Evaluation of Hepatic Glucose Production in a Polycystic Ovary Syndrome Mouse Model
DOI:

09:44 min

March 05, 2022

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Chapitres

  • 00:04Introduction
  • 01:00Preparation of [6,6-2H2]glucose
  • 02:15Set-up of Infusion Experiments
  • 03:19Catheter Insertion
  • 04:24Infusion Set-up and First Infusion
  • 05:51Blood Sampling
  • 06:30Second Infusion
  • 07:13Analyses and Calculations
  • 08:07Résultats
  • 08:39Conclusion

Summary

Traduction automatique

This study describes the direct measurement of hepatic glucose production in a polycystic ovary syndrome mouse model by using a stable isotopic glucose tracer via tail vein in both fasting and glucose-rich states in tandem.

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