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Neuroscience

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JoVE Journal Neuroscience
Endovascular Perforation Model for Subarachnoid Hemorrhage Combined with Magnetic Resonance Imaging (MRI)
 

Endovascular Perforation Model for Subarachnoid Hemorrhage Combined with Magnetic Resonance Imaging (MRI)

Article DOI: 10.3791/63150-v • 06:30 min • December 16th, 2021
December 16th, 2021 •
*1, *1, 1, 1, 2,3, 2,3, 1, 1
1Department of Neurosurgery, Charité - Universitätsmedizin Berlin, corporate member of Freie Universität Berlin, and Humboldt-Universität zu Berlin, and Berlin Institute of Health, 2Department of Experimental Neurology and Center for Stroke Research Berlin, Charité - Universitätsmedizin Berlin, corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, 3NeuroCure Cluster of Excellence and Charité Core Facility 7T Experimental MRIs, Charité - Universitätsmedizin Berlin
* These authors contributed equally

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Automatic Translation

Here we present a standardized SAH mouse model, induced by endovascular filament perforation, combined with magnetic resonance imaging (MRI) 24 h after operation to ensure the correct bleeding site and exclude other relevant intracranial pathologies.

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Keywords: Endovascular Perforation Model Subarachnoid Hemorrhage Magnetic Resonance Imaging (MRI) Mouse Common Carotid Artery External Carotid Artery Internal Carotid Artery Prolene Filament ACA-MCA Bifurcation Subarachnoid Space
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